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Information in the news releases is current on the date of the announcement, but is subject to change without prior notice.
2004 Release
  December 17, 2004
Eisai Recieves A Positive Opinion for Zonegran(R) Marketing Authorization From European Committee For Medicinal Products for Human Use (CHMP)


  November 19, 2004
Notice Concerning Completion of the Acquisition of the Company's Own Shares through ToSTNeT-2


  November 18, 2004
Notice Concerning the Acquisition of the Company's Own Shares through ToSTNeT-2


  November 15, 2004
Eisai In-licenses Anti-hepatitis B Agent clevudine From Bukwang Pharm (South Korea)


  October 29, 2004
Eisai Reacquires Worldwide Rights for a Triazole-Type Anti-Fungal Agent


  October 29, 2004
Eisai Announces Establishment of its Pharmaceuticals Marketing Subsidiary in India


  October 28, 2004
Eisai Announces Establishment of its European Regional Headquarters (Holding Company) in the U.K.


  October 22, 2004
Eisai Receives Approvals for New Formulations of ARICEPT (R) (donepezil hydrochloride), Orally Disintegrating Tablet and Liquid Formulation in the U.S.


  August 27, 2004
Notice Concerning the Revision of Eisai Co., Ltd. and Consolidated Subsidiaries Quarterly Financial Report for the Period Ended June 30, 2004


  August 5, 2004
Eisai Launches SAHNE WHITE R, A Medicated Skin Cream that Provides Protection Against Spots and Produces Smooth Skin


  July 30, 2004
Eisai's German Pharmaceuticals Marketing Subsidiary Starts Promotion of AstraZeneca's ENTOCORT R, a locally acting Glucocorticosteroid for Inflammatory Bowel Diseases


  July 30, 2004
Notice Concerning Acquisition of the Company's Own Shares


  July 8, 2004
Eisai Receives European Marketing Authorization for PARIET R(rabeprazole sodium) for Zollinger-Ellison Syndrome


  July 1, 2004
Notice Concerning Stock Options (Stock Acquisition Rights) Including the Amount Paid In Upon the Exercise of Stock Options


  June 30, 2004
Eisai Launches the First Treatment in Japan for Apnea of Prematurity Low Concentration Aminophylline, APNISSION R Injection 15mg


  June 28, 2004
Eisai's Statement to AD2000 Clinical Trial Led By the Collaborative Group of University of Birmingham


  June 28, 2004
Eisai Launches New Formulation of ARICEPT R, Rapid Disintegration Tablet, in Japan


  June 24, 2004
Notice on Allotment of Stock Options (Stock Acquisition Rights)


  June 18, 2004
Sanko Junyaku Co., Ltd., Subsidiary of Eisai Co., Ltd., to Launch New DCP Diagnostic Test Kit for Hepatocellular Carcinoma (HCC), LUMIPULSE PIVKA-II EISAI


  May 31, 2004
Eisai Submits MAA for New Formulation of ARICEPT R (donepezil hydrochloride), Liquid Formulation in the European Union


  May 12, 2004 Eisai Launches SACLON (R) & SACLON (R) Tablets with Increased Ingredients for Restoration of Damaged Stomach Mucosa and Acid Neutralization


  May 11, 2004 Notice on Providing Stock Options in the Form of New Stock Issuance


  May 11, 2004 Notice Concerning the Spin off of the Machinery Division of Eisai Co., Ltd


  May 7, 2004 Amendment of the Co-Development, Licensing and Supply Agreement for the Obesity Management Agent KES524


  April 23, 2004 ARICEPT (R) Application for Vascular Dementia is Withdrawn in the European Union


  April 21, 2004 PARIET (R) (rabeprazole sodium) Approved for On-Demand Therapy of Symptomatic GORD in the European Union


  April 19, 2004 Eisai Launches MENTEC(R) HERB for Irritation-Associated Fatigue and Headache


  April 2, 2004 Eisai's German Pharmaceuticals Marketing Subsidiary and GlaxoSmithKline Sign a Promotion Agreement for IMUREK(R), an Immunosuppressant


  March 31, 2004 Eisai acquires anti-epileptic drug Zonegran(R) (zonisamide) from Elan in North America and Europe


  March 1, 2004 Eisai Launches CHOCOLA(R) BB DRINK II, A New Vitamin B2 Drink for Alleviation of Skin Roughness


  February 25, 2004 Announcement on the Adoption of "Company with Committees System"


  February 25, 2004 Integration and Reorganization of Eisai's Machinery Operations


  February 10, 2004 E2000, Transdermal Muscle Relaxant Application Withdrawn in Japan


  February 9, 2004 Eisai Announces In-Licensing Agreement with Novartis for Rufinamide, A New Antiepileptic Agent


  February 3, 2004 Notice Concerning Completion of the Acquisition of the Company's Own Shares through ToSTNeT-2


  February 2, 2004 Notice Concerning the Acquisition of the Company's Own Shares through ToSTNeT-2


  January 30, 2004 Eisai Commences Another US Legal Action Over Aciphex(R) ANDA Filing


  January 15, 2004 Eisai Launches JUSTAT (R) Family of Products, Athlete's Foot and Ringworm Treatments


  January 7, 2004 Eisai Inc., a U.S. Subsidiary of Eisai Co., Ltd., Assumes All Distribution Responsibilities for ACIPHEX (R)


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